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Bevantolol hydrochloride
CAS No. 42864-78-8
Bevantolol hydrochloride ( NC-1400 hydrochloride )
产品货号. M21186 CAS No. 42864-78-8
Bevantolol Hydrochloride 是一种 β1-肾上腺素受体拮抗剂，可治疗心绞痛和高血压。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥284 | 有现货 |
|
| 25MG | ￥551 | 有现货 |
|
| 50MG | ￥786 | 有现货 |
|
| 100MG | ￥1239 | 有现货 |
|
| 200MG | ￥1855 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Bevantolol hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述Bevantolol Hydrochloride 是一种 β1-肾上腺素受体拮抗剂，可治疗心绞痛和高血压。
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产品描述Bevantolol hydrochloride is a β1-adrenoceptor?antagonist that treatment angina pectoris and?hypertension.(In Vitro):Bevantolol hydrochloride has a pKi of 6.23 for β2-adrenergic receptor.(In Vivo):Bevantolol hydrochloride (200 mg/kg; PO by water; for 6 weeks) produces a significant decrease in the expression level of β1 adrenoceptor mRNA.
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体外实验Bevantolol hydrochloride has a pKi of 6.23 for β2-adrenergic receptor.
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体内实验Bevantolol hydrochloride (200 mg/kg; PO by water; for 6 weeks) produces a significant decrease in the expression level of β1 adrenoceptor mRNA. Animal Model:Male Wistar rats weighing 250-300 g Dosage:200 mg/kg Administration:PO by water; for 6 weeks Result:Produced a significant decrease in the expression level of β1 adrenoceptor mRNA.
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同义词NC-1400 hydrochloride
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通路Angiogenesis
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靶点Adrenergic Receptor
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受体β1-adrenoceptor
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研究领域Cardiovascular Disease
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适应症Essential hypertension
化学信息
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CAS Number42864-78-8
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分子量381.9
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分子式C20H28ClNO4
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纯度>98% (HPLC)
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溶解度DMSO:76 mg/mL (199.01 mM)Ethanol:61 mg/mL (159.73 mM)H2O:52 mg/mL (136.16 mM)
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SMILESCOc1ccc(CCNCC(O)COc2cccc(C)c2)cc1OC.Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1.Noshiro T Miura Y Yoshinaga K et al. Clinical evaluation of bevantolol hydrochloride in patients with severe hypertension. The Cooperative Study Group on Bevantolol in Japan[J]. International Journal of Clinical Pharmacology & Therapeutics 1995 33(4):240-245.
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